Van Looy won the 1960 World Championship Road Race in front of Andre Darrigade of France and Pino Cerami of Belgium.
Van Looy also won the event in 1961, in front of Nino Defilippis of Italy and Raymond Poulidor of France.
Van Looy was also 2nd in 1956 behind Rik Van Steenbergen of Belgium, and 2nd in 1963 behind Benoni Beheyt of Belgium.
In addition, Van Looy was 4th in 1957 behind Rik Van Steenbergen of Belgium, Louison Bobet of France, and Andre Darrigade of France.
In other one-day races, Van Looy won the Paris-Tours in 1959 and 1967, the Ghent-Wevelgem in 1956, 1957, and 1962, plus the Fleche Wallone in 1968.
In the Grand Tours, Van Looy won the Points Jersey in the 1963 Tour de France and the Mountains Jersey in the 1960 Giro d’Italia.
In the Vuelta a Espana, Van Looy was 3rd in 1959 behind Antonio Suarez and Jose Segu of Spain, and was 3rd in 1965 behind Rolf Wolfshohl of Germany and Raymond Poulidor of France. Van Looy also won the Points Jerseys in those years as well.
Van Looy’s career spanned eighteen seasons beginning at age 19 in late 1953 and ending at age 36 in 1970. During this time, he racked up an impressive 419 professional road victories.